Molecules

RTK(pY)

RTK pY

PLCgamma1(nSH2,Tyr783~u~p,cSH2,core~inactive~active)

PLCgamma1 nSH2 Tyr783 u p cSH2 core inactive active

Species

RTK(pY)

RTK pY

PLCgamma1(nSH2,Tyr783~u,cSH2!1,core~inactive!1)

PLCgamma1 nSH2 Tyr783 u cSH2 core inactive

Observables

O0_RTK_tot RTK()

RTK ?pY

O0_PLCgamma1_tot PLCgamma1()

PLCgamma1 ?nSH2 Tyr783 u ?p ?cSH2 core inactive ?active

O0_PLCgamma1_active PLCgamma1(core~active!?)

PLCgamma1 ?nSH2 Tyr783 u ?p ?cSH2 core ?active

O0_PLCgamma1_inactive PLCgamma1(core~inactive!?)

PLCgamma1 ?nSH2 Tyr783 u ?p ?cSH2 core ?inactive

O0_PLCgamma1_pTyr783 PLCgamma1(Tyr783~p!?)

PLCgamma1 ?nSH2 Tyr783 ?p ?cSH2 core inactive ?active

O0_PLCgamma1_dpTyr783 PLCgamma1(Tyr783~u!?)

PLCgamma1 ?nSH2 Tyr783 ?u ?cSH2 core inactive ?active

O0_PLCgamma1_RTK_bound_inactive RTK(pY!1).PLCgamma1(nSH2!1,core~inactive!?)

RTK pY PLCgamma1 nSH2 Tyr783 u ?p ?cSH2 core ?inactive

O0_PLCgamma1_RTK_bound RTK(pY!1).PLCgamma1(nSH2!1)

RTK pY PLCgamma1 nSH2 Tyr783 u ?p ?cSH2 core inactive ?active

O0_PLCgamma1_cytosol PLCgamma1(nSH2,core~inactive!?)

PLCgamma1 nSH2 Tyr783 u ?p ?cSH2 core ?inactive

Reaction Rules

RTK(pY) + PLCgamma1(nSH2,core~active) -> RTK(pY!1).PLCgamma1(nSH2!1,core~active)

RTK ⬇pY ⬇ PLCgamma1 ⬇nSH2 Tyr783 u ?p ?cSH2 core active

RTK(pY) + PLCgamma1(nSH2,core~inactive!?) -> RTK(pY!1).PLCgamma1(nSH2!1,core~inactive!?)

RTK ⬇pY ⬇ PLCgamma1 ⬇nSH2 Tyr783 u ?p ?cSH2 core ?inactive

RTK(pY!1).PLCgamma1(nSH2!1) -> RTK(pY) + PLCgamma1(nSH2)

RTK ⬆pY ⬆ PLCgamma1 ⬆nSH2 Tyr783 u ?p ?cSH2 core inactive ?active

RTK(pY!1).PLCgamma1(nSH2!1,Tyr783~u!?) -> RTK(pY!1).PLCgamma1(nSH2!1,Tyr783~p!?)

RTK pY PLCgamma1 nSH2 Tyr783 ?u p take all branches, once each, in any order⬇ ?cSH2 core inactive ?active

PLCgamma1(Tyr783~p) -> PLCgamma1(Tyr783~u)

PLCgamma1 ?nSH2 Tyr783 u p take one or more branches, once each, in any order⬆ ?cSH2 core inactive ?active

PLCgamma1(cSH2!1,core~inactive!1) -> PLCgamma1(cSH2,core~inactive)

PLCgamma1 ?nSH2 Tyr783 u ?p ⬆cSH2 core ⬆inactive

PLCgamma1(cSH2,core~inactive) -> PLCgamma1(cSH2!1,core~inactive!1)

PLCgamma1 ?nSH2 Tyr783 u ?p ⬇cSH2 core ⬇inactive

PLCgamma1(Tyr783~p,cSH2) -> PLCgamma1(Tyr783~p!1,cSH2!1)

PLCgamma1 ?nSH2 Tyr783 ⬇p ⬇cSH2 core inactive ?active

RTK(pY!1).PLCgamma1(nSH2!1,core~inactive) -> RTK(pY!1).PLCgamma1(nSH2!1,core~active)

RTK pY PLCgamma1 nSH2 Tyr783 u ?p ?cSH2 core inactive active take all branches, once each, in any order⬇

PLCgamma1(nSH2,core~inactive) -> PLCgamma1(nSH2,core~active)

PLCgamma1 nSH2 Tyr783 u ?p ?cSH2 core inactive active take all branches, once each, in any order⬇

PLCgamma1(core~active) -> PLCgamma1(core~inactive)

PLCgamma1 ?nSH2 Tyr783 u ?p ?cSH2 core inactive active take one or more branches, once each, in any order⬆

PLCgamma1(Tyr783~p!1,cSH2!1) -> PLCgamma1(Tyr783~p,cSH2)

PLCgamma1 ?nSH2 Tyr783 ⬆p ⬆cSH2 core inactive ?active