Molecules

Lext(p,n~345~346~347~348~349~350~351~352~353~354~355)

Lext p n 345 346 347 348 349 350 351 352 353 354 355

Pit(s~p~e,l1,l2,l3,l4,l5,l6,l7,l8,l9,l10)

Pit s p e l1 l2 l3 l4 l5 l6 l7 l8 l9 l10

Lint(n~345~346~347~348~349~350~351~352~353~354~355)

Lint n 345 346 347 348 349 350 351 352 353 354 355

mRNA()

mRNA

GFP()

GFP

Trash()

Trash

I()

I

Timer()

Timer

Species

Lext(p,n~345)

Lext p n 345

Lext(p,n~346)

Lext p n 346

Lext(p,n~347)

Lext p n 347

Lext(p,n~348)

Lext p n 348

Lext(p,n~349)

Lext p n 349

Lext(p,n~350)

Lext p n 350

Lext(p,n~351)

Lext p n 351

Lext(p,n~352)

Lext p n 352

Lext(p,n~353)

Lext p n 353

Lext(p,n~354)

Lext p n 354

Lext(p,n~355)

Lext p n 355

Pit(s~p,l1,l2,l3,l4,l5,l6,l7,l8,l9,l10)

Pit s p l1 l2 l3 l4 l5 l6 l7 l8 l9 l10

mRNA()

mRNA

GFP()

GFP

I()

I

Timer()

Timer

Observables

Lext Lext(p,n)

Lext p n

Pit Pit(s~p)

Pit s p ?l1 ?l2 ?l3 ?l4 ?l5 ?l6 ?l7 ?l8 ?l9 ?l10

Endo Pit(s~e)

Pit s e ?l1 ?l2 ?l3 ?l4 ?l5 ?l6 ?l7 ?l8 ?l9 ?l10

Lint Lint()

Lint n 345 346 347 348 349 350 351 352 353 354 ?355

mRNA mRNA()

mRNA

GFP GFP()

GFP

TimerCount Timer()

Timer

Reaction Rules

Lext(p,n) -> Trash()

Lext p n degraded Trash synthesized

Lext(p,n) + Pit(s~p,l1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lext(p!1,n).Pit(s~p,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) + Pit(s~p,l1,l2,l3,l4,l5,l6,l7,l8,l9,l10)

Lext p n ⬇ Pit s p l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 Pit s p l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 synthesized

Lext(p,n) + Lext(p!1,n).Pit(s~p,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3,l4,l5,l6,l7,l8,l9,l10)

Lext ⬇p n ⬇ Lext p n Pit s p l1 ⬇l2 l3 l4 l5 l6 l7 l8 l9 l10

Lext(p,n) + Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4,l5,l6,l7,l8,l9,l10)

Lext ⬇p n ⬇ Lext p n Lext p n Pit s p l1 l2 ⬇l3 l4 l5 l6 l7 l8 l9 l10

Lext(p,n) + Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4,l5,l6,l7,l8,l9,l10) -> Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5,l6,l7,l8,l9,l10)

Lext ⬇p n ⬇ Lext p n Lext p n Lext p n Pit s p l1 l2 l3 ⬇l4 l5 l6 l7 l8 l9 l10

Lext(p,n) + Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5,l6,l7,l8,l9,l10) -> Lext(p!5,n).Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5!5,l6,l7,l8,l9,l10)

Lext ⬇p n ⬇ Lext p n Lext p n Lext p n Lext p n Pit s p l1 l2 l3 l4 ⬇l5 l6 l7 l8 l9 l10

Lext(p,n) + Lext(p!5,n).Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5!5,l6,l7,l8,l9,l10) -> Lext(p!6,n).Lext(p!5,n).Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5!5,l6!6,l7,l8,l9,l10)

Lext ⬇p n ⬇ Lext p n Lext p n Lext p n Lext p n Lext p n Pit s p l1 l2 l3 l4 l5 ⬇l6 l7 l8 l9 l10

Lext(p,n) + Lext(p!6,n).Lext(p!5,n).Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5!5,l6!6,l7,l8,l9,l10) -> Lext(p!7,n).Lext(p!6,n).Lext(p!5,n).Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5!5,l6!6,l7!7,l8,l9,l10)

Lext ⬇p n ⬇ Lext p n Lext p n Lext p n Lext p n Lext p n Lext p n Pit s p l1 l2 l3 l4 l5 l6 ⬇l7 l8 l9 l10

Lext(p!1,n).Pit(s~p,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lext(p!1,n).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10)

Lext p n Pit s p e take all branches, once each, in any order⬇ l1 l2 l3 l4 l5 l6 l7 l8 l9 l10

Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lext(p!2,n).Lext(p!1,n).Pit(s~e,l1!1,l2!2,l3,l4,l5,l6,l7,l8,l9,l10)

Lext p n Lext p n Pit s p e take all branches, once each, in any order⬇ l1 l2 l3 l4 l5 l6 l7 l8 l9 l10

Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4,l5,l6,l7,l8,l9,l10) -> Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~e,l1!1,l2!2,l3!3,l4,l5,l6,l7,l8,l9,l10)

Lext p n Lext p n Lext p n Pit s p e take all branches, once each, in any order⬇ l1 l2 l3 l4 l5 l6 l7 l8 l9 l10

Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5,l6,l7,l8,l9,l10) -> Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~e,l1!1,l2!2,l3!3,l4!4,l5,l6,l7,l8,l9,l10)

Lext p n Lext p n Lext p n Lext p n Pit s p e take all branches, once each, in any order⬇ l1 l2 l3 l4 l5 l6 l7 l8 l9 l10

Lext(p!5,n).Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~p,l1!1,l2!2,l3!3,l4!4,l5!5,l6,l7,l8,l9,l10) -> Lext(p!5,n).Lext(p!4,n).Lext(p!3,n).Lext(p!2,n).Lext(p!1,n).Pit(s~e,l1!1,l2!2,l3!3,l4!4,l5!5,l6,l7,l8,l9,l10)

Lext p n Lext p n Lext p n Lext p n Lext p n Pit s p e take all branches, once each, in any order⬇ l1 l2 l3 l4 l5 l6 l7 l8 l9 l10

Pit(s~e,l1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Trash()

Pit s e l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Trash synthesized

Lext(p!1,n~345).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~345)

Lext ⬆p n 345 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 345 synthesized

Lext(p!1,n~346).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~346)

Lext ⬆p n 346 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 346 synthesized

Lext(p!1,n~347).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~347)

Lext ⬆p n 347 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 347 synthesized

Lext(p!1,n~348).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~348)

Lext ⬆p n 348 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 348 synthesized

Lext(p!1,n~349).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~349)

Lext ⬆p n 349 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 349 synthesized

Lext(p!1,n~350).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~350)

Lext ⬆p n 350 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 350 synthesized

Lext(p!1,n~351).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~351)

Lext ⬆p n 351 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 351 synthesized

Lext(p!1,n~352).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~352)

Lext ⬆p n 352 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 352 synthesized

Lext(p!1,n~353).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~353)

Lext ⬆p n 353 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 353 synthesized

Lext(p!1,n~354).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~354)

Lext ⬆p n 354 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 354 synthesized

Lext(p!1,n~355).Pit(s~e,l1!1,l2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~355)

Lext ⬆p n 355 degraded ⬆ Pit s e ⬆l1 l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 355 synthesized

Lext(p!2,n~345).Lext(p!1,n~345).Pit(s~e,l1!1,l2!2,l3,l4,l5,l6,l7,l8,l9,l10) -> Lint(n~345) + Lint(n~345)

Lext ⬆p n 345 degraded ⬆ Lext ⬆p n 345 degraded ⬆ Pit s e ⬆l1 ⬆l2 l3 l4 l5 l6 l7 l8 l9 l10 degraded Lint n 345 synthesized Lint n 345 synthesized

Lint() -> Trash()

Lint n 345 346 347 348 349 350 351 352 353 354 ?355 degraded Trash synthesized

Lint(n~345) -> mRNA() + mRNA() + mRNA() + mRNA() + mRNA()

Lint n 345 degraded mRNA synthesized mRNA synthesized mRNA synthesized mRNA synthesized mRNA synthesized

Lint(n~346) -> mRNA() + mRNA() + mRNA() + mRNA() + mRNA()

Lint n 346 degraded mRNA synthesized mRNA synthesized mRNA synthesized mRNA synthesized mRNA synthesized

mRNA() -> Trash()

mRNA degraded Trash synthesized

mRNA() -> mRNA() + GFP()

mRNA GFP synthesized

GFP() -> Trash()

GFP degraded Trash synthesized

I() -> I() + Timer()

I Timer synthesized